p27 Polyclonal Antibody, 100ul[BT-AP06756] Pathway and Network Analysis Overexpression of BCL2L12 has been

Overexpression of BCL2L12 has been detected in a number of different cancers

The encoded protein may play a role in the developing kidney

It is highly homologous to the myelin protein zero and| in thymus-derived epithelial cell lines| is poorly soluble in nonionic detergents| strongly suggesting an association to the cytoskeleton

and (in human) retinal degeneration

and possibly in chromatin structure modification

p27 Polyclonal Antibody, 100ul[BT-AP06756] Pathway and Network Analysis Overexpression of BCL2L12 has beenCDKN1B encodes a cyclin dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A p21. The cyclin dependent kinase inhibitor 1B binds to and prevents the activation of cyclin E CDK2 or cyclin D CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the