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For instance, prolyl hydroxylases are one of those enzymes involved in collagen biosynthesis

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The expression of a novel LOX-related gene, named LOXC, has been detected in cartilage in vivo , which modulates the formation of collagenous extracellular matrix ( de novo multiple musculoskeletal tissues (i.e., cartilage, meniscus, tendons, and ligaments) as important regenerative strategies, which is mainly mediated through mechanisms of hypoxia-induced enhanced PYR crosslinking and increased tensile properties of collagen-rich tissues (Makris et al., 2014)

Originally developed for managing Type 2 diabetes, drugs like semaglutide and tirzepatide have exploded in popularity as weight-loss treatments, fueling a market that analysts project will reach tens of billions of dollars in the coming years