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Glucagon-like peptide 1 modulates calcium responses to glutamate and membrane depolarization in hippocampal neurons

It reports that body aches and musculoskeletal discomfort have been reported by some patients on GLP-1 receptor agonists including semaglutide, but says incidence and severity vary considerably and causality remains incompletely understood

Weight gain seemed inevitable, and every effort ended in frustration

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Some people report fewer nausea symptoms when injecting at night because sleep blunts awareness of early side effects

Are there possible side effects even with microdosing