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Semaglutide is a prescription medication that mimics the natural hormone GLP-1, which plays a role in regulating appetite, digestion, and blood sugar

Ji et al., 2010

TL;DR Mounjaro delivers 20.2% average body weight loss versus Wegovys 13.7% in the landmark SURMOUNT-5 head-to-head trial However, Wegovy costs less ($599.95/month cash vs $559.99 $799.99/month for Mounjaro) and is approved for cardiovascular disease risk reduction Mounjaro is a dual GIP/GLP 1 receptor agonist while Wegovy is GLP 1 only Both are prescription only medications requiring weekly injections with similar gastrointestinal side effects Choose Mounjaro for greater weight loss

The role of inflammasome-derived il-1 in driving il-17 responses