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The peptide also appears to influence neurotransmitter systems, particularly the dopaminergic and GABAergic pathways, which may contribute to its observed effects on neurological function and behavior

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Tryptophan supplementation has been shown to reduce stress-related behaviours in fish, such as aggression and hyperactivity, by increasing serotonin levels in the brain [89]

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Collection and processing of blood specimens Two sets of peripheral blood samples (~90 ml each set) were obtained by venipuncture from each patient and healthy control at -month intervals in accordance with previously described study protocols [44]