p300 Polyclonal Antibody, 50ul[BT-AP06775] High Speed Micro-Centrifuges The encoded protein is localized

The encoded protein is localized to the cytosol and mitochondria| and associates with membranes through an isoprenyl modification near the C-terminus

it is possible that they also have cytoplasmic functions

RNA polymerase II distal enhancer sequence-specific binding

This gene encodes a member of the a ubiquitously expressed transcription factor that controls cholesterol homeostasis by regulating transcription of sterol-regulated genes

and it exhibits overall 46% amino acid identity to E2F1

p300 Polyclonal Antibody, 50ul[BT-AP06775] High Speed Micro-Centrifuges The encoded protein is localizedEP300 encodes the adenovirus E1A associated cellular p300 transcriptional co activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP gene regulation by binding specifically to phosphorylated CREB protein. EP300 has also been identified as a co activator of HIF1A (hypoxia inducible factor 1 alpha), and