Raf-1(Phospho Thr269) Polyclonal Antibody, 50ul Hybridoma Antibody Sequencing Isoform 4 is also expressed

Isoform 4 is also expressed in Leydig cells

through which this receptor induces the activation of NF-kappa B and MAPK8/JNK

The protein functions by blocking glycolysis and directing the pathway into the pentose phosphate shunt

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Raf-1(Phospho Thr269) Polyclonal Antibody, 50ul Hybridoma Antibody Sequencing Isoform 4 is also expressedThis gene is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine specific protein kinases, ERK1 and ERK2.