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CITE2 Polyclonal Antibody, 20ul Gene Synthesis SENP2 (SUMO1/sentrin/SMT3 specific peptidase 2)

SKU: 98907396754

4.3
SEK97.20 SEK137.20

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CITE2 Polyclonal Antibody, 20ul Gene Synthesis SENP2 (SUMO1/sentrin/SMT3 specific peptidase 2)The protein encoded by this gene inhibits transactivation of HIF1A induced genes by competing with binding of hypoxia inducible factor 1 alpha to p300 CH1. Mutations in this gene are a cause of cardiac septal defects. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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Description

SENP2 (SUMO1/sentrin/SMT3 specific peptidase 2) is one of a group of enzymes that process newly synthesized SUMO1 into the conjugatable form and catalyze the deconjugation of SUMO1-containing species

5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor

some members of this family may be involved in embryogenesis

and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance

Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters

CITE2 Polyclonal Antibody, 20ul Gene Synthesis SENP2 (SUMO1/sentrin/SMT3 specific peptidase 2)The protein encoded by this gene inhibits transactivation of HIF1A induced genes by competing with binding of hypoxia inducible factor 1 alpha to p300 CH1. Mutations in this gene are a cause of cardiac septal defects. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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