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Pomalidomide 4-PEG1-amine - CAS# 2154342-56-8 050 The first class (DuP-753 sensitive)

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Pomalidomide 4-PEG1-amine - CAS# 2154342-56-8 050 The first class (DuP-753 sensitive)Pomalidomide 4 PEG1 amine, CAS No. 2154342 56 8, cereblon ligand with PEG linker and terminal amine for onward chemistry. Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG1 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. Product information CAS Number: 2154342 56 8 Molecular Weight: 396. 83

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Description

The first class (DuP-753 sensitive) represents approximately 85% of the total binding sites for AII and possesses a high affinity (IC50 of 92

84(4):e475-81

Enhanced optineurin E50K-TBK1 interaction evokes protein insolubility and initiates familial primary open-angle glaucoma

Formula: C15H20O3

2020 May 14

Pomalidomide 4-PEG1-amine - CAS# 2154342-56-8 050 The first class (DuP-753 sensitive)Pomalidomide 4 PEG1 amine, CAS No. 2154342 56 8, cereblon ligand with PEG linker and terminal amine for onward chemistry. Functionalized cereblon ligand for PROTAC research and development; incorporates an E3 ligase ligand plus a PEG1 linker with terminal amine ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D. Product information CAS Number: 2154342 56 8 Molecular Weight: 396. 83

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