Motesanib Diphosphate D8 dihydrochloride Chemical Name: N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}-N-(pyridin-2-yl)cyclohexanecarboxamide

Chemical Name: N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}-N-(pyridin-2-yl)cyclohexanecarboxamide

Tegafur is bioactivated to 5-FU by liver microsomal cytochrome P450 enzymes

ClH/c26-23(27-21-16-24-13-10-18(21)11-14-24)25-15-12-17-6-4-5-9-20(17)22(25)19-7-2-1-3-8-19

which may result in modulation of cell cycle protein expression

AEE-788 is an orally bioavailable multiple-receptor tyrosine kinase inhibitor

Motesanib Diphosphate D8 dihydrochloride Chemical Name: N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}-N-(pyridin-2-yl)cyclohexanecarboxamideMotesanib, also known as AMG 706, is the orally bioavailable multiple receptor tyrosine kinase inhibitor with potential antineoplastic activity. Motesanib selectively targets and inhibits vascular endothelial growth factor (VEGFR), platelet derived growth factor (PDGFR), kit, and Ret receptors, thereby inhibiting angiogenesis and cellular proliferation. Product information CAS Number: 857876 30 3 Molecular Weight: 569. 44 Formula: C22H29N5O9P2