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The plateau emerges when another bottleneck becomes dominant

BKhadkaD.PanditA.et al (2014)

Ionizing radiation to the hemicerebrum caused an increase in the levels of glutathione (GSH) and the activity of a GSH synthesizing enzyme, -glutamylcysteine synthetase (-GCS), and Cu,Zn-superoxide dismutase (Cu,Zn-SOD)

The copper chaperone ATOX1 is a particularly compelling target in this context

4.3 GPX4-GSH-cysteine axis protector SARS-CoV-2 infection disrupts the balance between the bodys oxidative and antioxidant systems, preventing the timely clearance of ROS

it's simply unnecessary