Cathepsin L Polyclonal Antibody, 100ul Centrifuges a transactivation domain enriched in
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Cathepsin L Polyclonal Antibody, 100ul Centrifuges a transactivation domain enriched inCathepsin L1 encoded by CTSL1 is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha 1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to
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