UVRAG Polyclonal Antibody, 50ul Organelle Studies Up-regulated upon mitogenic stimulation

Up-regulated upon mitogenic stimulation

This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH

vasoconstriction

Alternatively spliced transcript variants encoding different isoforms have been found for GYS1

It is also thought to contribute to tumor metastases by promoting cancer cell migration and invasion

UVRAG Polyclonal Antibody, 50ul Organelle Studies Up-regulated upon mitogenic stimulationThis gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1 PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left right axis malformation and mutations in this gene have been associated with colon cancer.